Studies on glucocorticoid hormone actions in the regulation of human amnion PGHS

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dc.contributor Zakar, T
dc.contributor Olson, DM
dc.date.accessioned 2012-01-30T06:41:20Z
dc.date.available 2012-01-30T06:41:20Z
dc.date.issued 1995
dc.identifier.citation Rep. Fert. Dev. (1995) 7(3): 517-520
dc.identifier.issn 1031-3613
dc.identifier.uri http://livestocklibrary.com.au/handle/1234/15870
dc.description.abstract The human amnion is an excellent model in which to study the regulation of the expression of prostaglandin endoperoxide H synthase-2 (PGHS-2) mRNA by glucocorticoids, as glucocorticoids can both stimulate and inhibit PGHS activity and can have their stimulatory effect reversed to an inhibitory one. Our studies suggest the presence of a glucocorticoid-induced inhibitory protein which affects the post-transcriptional activity of PGHS-2 mRNA. Glucocorticoid-induced expression of PGHS-2 mRNA may be dependent on protein phosphorylation.
dc.publisher CSIRO Publishing
dc.source.uri http://www.publish.csiro.au/?act=view_file&file_id=RD9950517.pdf
dc.title Studies on glucocorticoid hormone actions in the regulation of human amnion PGHS
dc.type Research
dc.description.version Journal article
dc.identifier.volume 7
dc.identifier.page 517-520
dc.identifier.issue 3


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